[Correlation Analysis of Platelet Aggregation Rate Detected by Platelet Analyzer, Platelet Aggregometer and Thromboelastography].

题目: 血小板分析仪、血小板聚集仪和血栓弹力图仪检测血小板聚集率. METHODS: The performance of platelet analyzer in platelet count and platelet aggregation function was evaluated. The platelet aggregation rate of 55 patients with type 2 diabetes mellitus (T2DM) before and after taking aspirin alone (32 cases) and clopidogrel alone (23 cases) was measured by thromboelastography, platelet aggregometer and platelet analyzer respectively, and the analytical results were compared. The correlation between the results measured by different instruments and equipment were further analyzed and the data were included in the statistical analysis. 方法: 对血小板分析仪在血小板计数和血小板聚集功能的性能方面进行评估；分别采用血栓弹力图仪、血小板聚集仪和血小板分析仪对55例2型糖尿病（T2DM）患者，单用阿司匹林（32例）、单用氯匹格雷（23例）前后血小板聚集率进行测定，并对检测结果进行比较，进一步分析不同仪器设备所测结果的相关性，将所得数据纳入统计学分析. 结果: 血小板分析仪日间和批内精密度均低于1/3总误差（7%），携带污染率为0.30%，在4.15×109/L至1379.95×109/L的线性范围内的回归方程斜率为1.02，R2=0.99，血小板计数所测结果与血小板参考方法的检测结果符合率达85%，符合行业标准要求。血栓弹力图仪、血小板聚集仪和血小板分析仪测定T2DM患者单用氯匹格雷和阿司匹林后血小板聚集率较服药前明显下降（P<0.01）. 结论: 血小板分析仪能够为临床检测血小板计数和聚集功能提供可靠、客观、准确的信息，并符合行业标准要求，且其与血小板聚集仪和血栓弹力图仪对血小板聚集率的检测结果相当.