GLUTATHION SYSTEM IN THE SERUM OF BLOOD RATS IN THE DYNAMICS OF FULL-THICKNESS WOUNDS AND WITH THE INFLUENCE OF THE NEW PHARMACOLOGICAL COMPOSITION WHICH CONTAIN MELANINE

The activity of enzymes of the glutathione link of the antioxidant system in rats with experimental full-thickness wound has been studied. It is established that in the serum of rats under the experimental model of the cut wound the level of recovered glutathione and glutathione reductase activity decreased, glutathione peroxidase and glutathione transferase activity increased. All investigated parameters normalized in dynamics after treatment with melanin.