Primary Survey of the Optimal Harvesting Period of Pinellia ternata (Thunb.) Breit.

[Objective] To detect the toxicity of R.trigyna water extracts in short term based on the acute toxicity test to mice.[Method] Effects of R.trigyna water extracts on the mice leukocyte were the greatest,but the two showed no linear relationship.The low and high dosages had little effects but the middle dosage had significant effects.R.trigyna water extracts had few effects on lymphocyt and monocyte,had great effects on neutrophil,had relatively small effects on erythrocyte except group D,and had no significant effects on hemoglobin.R.trigyna had no significant effects on the physical signs and activity condition of mice,which reduced the leukocyte and neutrophil in blood and led to the decrease of immune function.High dosage caused the liver toxicity and had no significant effects on kidney.[Conclusion] R.trigyna water extracts had certain toxicological effects on mice,and high dosage had great toxicity.