Microcavity Fiber SERS Probe Coated With Ag Nanoparticles For Detecting Antibiotic In Milk

2021 
In this paper, an Ag nanoparticles (AgNPs) modified multimode fiber (MMF) SERS probe prepared based on sol self-assembly method was proposed and fabricated. By adjusting the self-assembly time, different fiber SERS probes (AgNPs-MMF-x, x is the self-assembly time) were obtained. Using rhodamine 6G (R6G) solution as the probe molecule, the far-end performance of the prepared fiber SERS probe was studied, and the AgNPs-MMF-30 probe with obvious advantages in SERS performance was obtained. The limit of detection (LOD) for R6G was as low as 10-9 M, demonstrating the high sensitivity of AgNPs-MMF-30 probe. The enhancement factor (EF) of AgNPs-MMF-30 probe to 10-7 M R6G is about 1.36108. In addition, the AgNPs-MMF-30 probe has an outstanding reproducibility across the entire area with the maximum value of relative standard deviation (RSD) of less than 10.94%. The AgNPs-MMF-30 probe exhibit a long-term stability regarding Raman enhancement of up to 35 days. Importantly, the high-performance AgNPs-MMF-30 probe is further applied as a high sensitive SERS platform for the trace detection of antibiotic in milk. The fiber SERS probe has the characteristics of fast, effective, remote real-time detection and so on, so it has great potential application in biochemical sensing and food security.
    • Correction
    • Source
    • Cite
    • Save
    • Machine Reading By IdeaReader
    36
    References
    2
    Citations
    NaN
    KQI
    []