Preparation of a fluorous chiral BINAP and application to an asymmetric Heck reaction

Abstract Fluorous chiral BINAP (( R )-F 13 BINAP) was prepared and was applied to an asymmetric Heck reaction. The enantioselectivity was similar in BTF homogeneous system (90% ee) to that of the original non-fluorous reaction and marginally higher in benzene and FC-72 biphasic system (93% ee) than that of the original non-fluorous one.