Inhibition of YAP suppresses CML cell proliferation and enhances efficacy of imatinib in vitro and in vivo
2016
Background
Yes-associated protein (YAP), an essential component of Hippo pathway, was identified as an oncoprotein which participated in the progression of various malignancies. However, its role in chronic myeloid leukemia (CML) remains to be further clarified.
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