Comparative study of wild Pinelliae rhizome and cultivated Pinelliae rhizome on cough expectorant

Objective To compare the differences of wild Pinelliae rhizome and cultivated Pinelliae rhizome in same provenance for cough expectorant,and provide evidence for cultivation of Pinelliae rhizome.Methods The same source of fresh and preserved wild Pinelliae rhizome and fresh cultivated Pinelliae rhizome were prepared as cum alumine according to Chinese Pharmacopoeia.1) Experimental cough in mice induced by ammonia:to compare the relieving cough of the wild and cultivated Pinelliae rhizome with the indicators of incubation period inducing cough and frequency coughing in three minutes.2) Experimental phenol red excretion in mice trachea:to evaluate the difference of wild and cultivated Pinelliae rhizome removing the phlegm with the excreting phenol red from trachea in mice.Results 1) Compared with the control group,the fresh wild,the preserved wild and cultivated Pinelliae rhizome extended to cough latency reduced the frequency of cough,the difference was significant(P0.01 or P0.05).2) Compared with the control group,the fresh wild,the preserved wild and cultivated Pinelliae rhizome were effective to remove the phlegm(P0.001 or P0.01).Conclusion The fresh wild is superior to both the preserved wild and the in relieving cough,and the wild was superior to the cultivated,while the preserved wild was superior to the fresh wild Pinelliae rhizome.