PTEN and rapamycin inhibiting the growth of K562 cells through regulating mTOR signaling pathway.
2008
Objective
To investigate, in vitro, the regulatory effects of tumor-suppressing gene PTEN on mTOR (mammalian target of rapamycin) signaling pathway, the effects of transfected PTEN and rapamycin on the growth inhibition, and apoptosis induction for human leukemia cell line K562 cells.
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