X-ray bi-prism interferometry - A design study of proposed novel hardware.

2021 
PURPOSE Advances in X-ray phase-contrast imaging can obtain excellent soft-tissue contrast of phase-shift, attenuation, and small angle scatter. Here we present fringe patterns for different design parameters of X-ray bi-prism interferometry imaging systems. Our aim is to develop bi-prism interferometry imaging systems with excellent polychromatic performance that produce high-contrast fringes with spatially incoherent X-ray illumination. We also introduce a novel X-ray tube design that uses temporal multiplexing to provide simultaneous virtual "electronic phase stepping" that replace "mechanical phase stepping" popular with grating-based interferometry setups. METHODS In our investigation we develop expressions for the irradiance distribution pattern of a bi-prism interferometer comprised of multiple point sources and multiple bi-prisms. These expressions are used to plot fringe patterns for X-ray design parameters including size of point source, number of point sources, and point source separation; and bi-prism design parameters including material, angle, number of bi-prisms, period, and bi-prism array to X-ray source and to detector distances. RESULTS Results show that the fringe patterns for a bi-prism interferometry system are not longitudinally periodic as with grating interferometers that produce a Talbot-Lau carpet. It is also shown that at 59 keV X-rays the bi-prism material should be something comparable to nickel to obtain reasonable fringe visibility. CONCLUSION The irradiance distribution pattern demonstrates that bi-prism interferometry may provide comparable or improved fringe visibility to that of gratings. Special care is given to present our findings within the context of previous advancements. A single-shot image acquisition approach using a temporal multiplexed, high-power X-ray source provides virtual electronic phase stepping without focal spot sweeping. This provides multiple images, each at the same exposure and the same projection view, from different fringe locations that allow one to derive the attenuation, phase, and dark-field images of the sample without mechanical phase stepping of a grating. This article is protected by copyright. All rights reserved.
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