In silico identification and experimental validation of amino acid motifs required for the Rho-of-plants GTPase-mediated activation of receptor-like cytoplasmic kinases

Dézi Bianka Lajkó,Ildikó Valkai,Mónika Domoki,Dalma Ménesi,Györgyi Ferenc,Ferhan Ayaydin,Attila Fehér

In silico identification and experimental validation of amino acid motifs required for the Rho-of-plants GTPase-mediated activation of receptor-like cytoplasmic kinases

2018

Dézi Bianka Lajkó
Ildikó Valkai
Mónika Domoki
Dalma Ménesi
Györgyi Ferenc
Ferhan Ayaydin
Attila Fehér

Key message Several amino acid motifs required for Rop-dependent activity were found to form a common surface on RLCKVI_A kinases. This indicates a unique mechanism for Rho-type GTPase-mediated kinase activation in plants.

Keywords:

Protein–protein interaction
Genetics
Arabidopsis thaliana
Cytoplasm
GTPase
Biochemistry
Amino Acid Motifs
Biology
Kinase
In silico
Receptor
Phosphorylation
Protein domain
Peptide sequence
GTP-binding protein regulators
Plasma protein binding

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