Sonomolides A and B, New Broad Spectrum Antifungal Agents Isolated from a Coprophilous Fungus.

Sandra A. Morris,James E. Curotto,Deborah L. Zink,Sarah Dreikorn,Rosalind G. Jenkins,Gerald F. Bills,John R. Thompson,Francisca Vicente,Angela Basilio,Jerrold M. Liesch,Robert E. Schwartz

Sonomolides A and B, New Broad Spectrum Antifungal Agents Isolated from a Coprophilous Fungus.

1996

Sandra A. Morris
James E. Curotto
Deborah L. Zink
Sarah Dreikorn
Rosalind G. Jenkins
Gerald F. Bills
John R. Thompson
Francisca Vicente
Angela Basilio
Jerrold M. Liesch
Robert E. Schwartz

Abstract Two novel amifungal agents, sonomolides A ( 1 ) and B ( 2 ), have been isolated and their structures determined mainly by nmr. Both compounds show inhibitory activity against a broad range of fungal pathogens.

Keywords:

Fungus
Terpene
Organic chemistry
Antifungal
Chemistry
broad spectrum

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