Prediction and modelling studies for capacity factors of a group of dihydropyridines in micellar liquid chromatography with hybrid eluents

Empirical equations were used to predict the retention behaviour of a group of twenty-seven dihydropyridines in Micellar Liquid Chromatography with hybrid eluents on an octylsilica column. A theoretical model was also used to study their retention mechanism. Hexadecyltrimethylammonium bromide and sodium dodecyl sulphate were used as surfactants in the mobile phase and as organic modifiers n-propanol and n-butanol were employed.