Cannabinoid and kappa opioid receptors reduce potassium K current via activation of G(s) proteins in

A hand-held device for body care, in particular for tooth care and mouth care, which comprises a device casing serving as grip member, a hydraulic piston motor, an instrument holder alternatingly drivable by the motor, a liquid duct connectable to an external liquid pump, for feeding the hydraulic piston motor, and at least one adjustable valve for energizing and stopping the hydraulic motor. The device is adapted for use with treatment instruments which can be attached to the instrument holder in an interchangeable manner, in particular tooth brushes or spraying nozzles.