Ancient complement and lineage-specific evolution of the Sec7 ARF GEF proteins in eukaryotes

Shweta V. Pipaliya,Alexander Schlacht,Christen M. Klinger,Richard A. Kahn,Joel B. Dacks

Ancient complement and lineage-specific evolution of the Sec7 ARF GEF proteins in eukaryotes

2019

Shweta V. Pipaliya
Alexander Schlacht
Christen M. Klinger
Richard A. Kahn
Joel B. Dacks

Sec7 domain-containing ARF GEF proteins activate ARF GTPases to modulate a variety of processes in the endomembrane pathway. Comparative genomics and phylogenetic analyses of 506 Sec7 proteins in 7...

Keywords:

Cell biology
Evolutionary biology
Biology
Opisthokont
GTPase
Alveolate
Haptophyte
Guanine nucleotide exchange factor
Phylogenetic tree
Subfamily
Ankyrin

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