Interleukin-10 Gene-Modified Dendritic Cell-Induced Type 1 Regulatory T Cells Induce Transplant-Tolerance and Impede Graft Versus Host Disease After Allogeneic Stem Cell Transplantation

Jiangbo Wan,Fang Huang,Siguo Hao,WeiWei Hu,Chuanxu Liu,Wenhao Zhang,Xiaohui Deng,Linjun Chen,Liyuan Ma,Rong Tao

Interleukin-10 Gene-Modified Dendritic Cell-Induced Type 1 Regulatory T Cells Induce Transplant-Tolerance and Impede Graft Versus Host Disease After Allogeneic Stem Cell Transplantation

2017

Jiangbo Wan
Fang Huang
Siguo Hao
WeiWei Hu
Chuanxu Liu
Wenhao Zhang
Xiaohui Deng
Linjun Chen
Liyuan Ma
Rong Tao

Background/Aims: Tr1 cells can induce peripheral tolerance to self- and foreign antigens, and have been developed as a therapeutic tool for the induction of toler

Keywords:

Dendritic cell
Follicular dendritic cells
Stem cell
Immunology
Graft-versus-host disease
Immune tolerance
Antigen-presenting cell
Interleukin 12
Biology
Peripheral tolerance

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