A Systematic Evaluation of Antibody Modification and 89Zr-Radiolabeling for Optimized Immuno-PET.

Sai Kiran Sharma,Jonathan M Glaser,Kimberly J. Edwards,Elaheh Khozeimeh Sarbisheh,Akam K Salih,Jason S. Lewis,Eric W. Price

A Systematic Evaluation of Antibody Modification and 89Zr-Radiolabeling for Optimized Immuno-PET.

2020

Sai Kiran Sharma
Jonathan M Glaser
Kimberly J. Edwards
Elaheh Khozeimeh Sarbisheh
Akam K Salih
Jason S. Lewis
Eric W. Price

Immuno-PET using desferrioxamine (DFO)-conjugated zirconium-89 ([89Zr]Zr4+)-labeled antibodies is a powerful tool used for preclinical and clinical molecular imaging. However, a comprehensive study...

Keywords:

Antibody
Molecular imaging
Chemistry
Biochemistry
Tris
Surface plasmon resonance
HEPES
Positron emission tomography
Radioimmunoconjugate
Nuclear magnetic resonance
immuno pet

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