Protein dynamics during presynaptic-complex assembly on individual single-stranded DNA molecules

Bryan Gibb,Ling F. Ye,Youngho Kwon,Hengyao Niu,Patrick Sung,Eric C. Greene

Protein dynamics during presynaptic-complex assembly on individual single-stranded DNA molecules

2014

Bryan Gibb
Ling F. Ye
Youngho Kwon
Hengyao Niu
Patrick Sung
Eric C. Greene

New single-molecule imaging analyses reveal how dynamic interactions of RPA, Rad52 and Rad51 on single-stranded DNA direct assembly of the presynaptic complex that promotes strand invasion during homologous recombination.

Keywords:

Strand invasion
Saccharomyces cerevisiae
DNA
Homologous recombination
Replication protein A
RAD52
RAD51
Binding site
Molecular biology
Biology

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