Method Development for Quantitative Determination of the Gaba Derivative Solifen

L. A. Smirnova,A. F. Ryabukha,K. A. Kuznetsov,M. V. Velikopol’skaya,V. N. Perfilova,O. S. Vasil’eva,I. N. Tyurenkov,L. M. Ganicheva

Method Development for Quantitative Determination of the Gaba Derivative Solifen

2020

L. A. Smirnova
A. F. Ryabukha
K. A. Kuznetsov
M. V. Velikopol’skaya
V. N. Perfilova
O. S. Vasil’eva
I. N. Tyurenkov
L. M. Ganicheva

An HPLC method for quantitative determination of the new biologically active GABA derivative Solifen was developed. The method sensitivity, compound retention time and UV absorption maximum were determined. The optimum extractant for the compound from biological samples was determined.

Keywords:

method development
Organic chemistry
Chemistry
uv absorption
quantitative determination
hplc method
retention time
Chromatography
pharmacology toxicology

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