Derivatives of 3,4-dihydro-pyrrolo [1,2-a] pyrazine-2,8 (1H) -dicarboxamide, their preparation and therapeutic use thereof

Compounds corresponding to the general formula (I): Formula ** ** in which R2 represents: - a group C1-10 alkyl, C3-7cycloalkyl-C1-6alkyl, C1-6tio alkyl-C1-10 alkyl, C1-6 alkoxy-C1-10 alkyl, C1-10 hydroxyalkyl, hydroxy-C1-6 alkyl-C1-6 cycloalkyl C3-7 alkyl, C1-10 fluoroalkyl, C1-10 alkyl-oxyimino-C1-10alkyl , - a hydroxy-C3-10 cycloalkyl C3-10 cycloalkyl group, C3-10 fluorociclloalquilo, - a C3-7 cycloalkyl group which may be substituted with one or two groups independently selected from C1-6 alkyl, C3-7 cycloalkyl, hydroxyl, C1-10 fluoroalkyl, and C1-10 alkyl-oxyimino, - a heterocyclic group comprising 3 to 8 carbon atoms and at least one heteroatom selected from nitrogen, oxygen, sulfur and oxide or sulfur dioxide form, being this heterocyclic group possibly substituted with one or more groups from hydroxyl, C1-6 alkyl, C1-6 hydroxyalkyl, C1-6 fluoroalkyl, this heterocyclic group being selected from ox ethanyl, tetrahydrofuryl, tetrahydro-2H-pyranyl, oxepanyl, thietanyl, tetrahydrothiophenyl, tetrahydro-2Htiopiranilo, thiepanyl, 1,1-dioxidotietanilo, 1,1-dioxidotetrahidrotiofenilo, 1,1-dioxidotetrahydro-2Htiopiranilo and 1,1-dioxidotiepanilo; - a C1-10 alkyl group substituted by a heterocyclic group comprising 3 to 8 carbon atoms and at least one heteroatom selected from nitrogen, oxygen, sulfur and form oxide or sulfur dioxide, this heterocyclic group possibly being substituted with one or more groups from hydroxyl, C1-6 alkyl, C1-6 hydroxy alkyl, C1-6 fluoroalkyl, this heterocyclic group being selected from oxetanyl, tetrahydrofuryl, tetrahydro-2H-pyranyl, oxepanyl, thietanyl, tetrahydrothiophenyl, tetrahydro-2H- thiopyranyl, thiepanyl, 1,1-dioxidotietanilo, 1,1-dioxidotetrahidrotiofenilo, 1,1- dioxidotetrahydro-2H-thiopyranyl and 1,1-dioxidotiepanilo; X6 represents a hydrogen atom, fluorine, chlorine or bromine atom or a C1-6 alkyl, C3-7 cycloalkyl, C1-6 cycloalkyl C3-7 alkyl, C1-6 fluoroalkyl or cyano; R7 represents a phenyl group or a naphthyl group, optionally substituted with one or more substituents X7, which may be identical or different, selected independently; X7 represents: - a halogen atom chosen from fluorine, chlorine and bromine, or a group selected from: - hydroxy, - C1-6alkyl, C3-7cycloalkyl, C3-7cycloalkyl-C1-6alkyl, - hydroxy -C1-6alkyl, hydroxy-C3-7 cycloalkyl, C1-6 cycloalkyl C3-7 hydroxy-alkyl, - C1-6 alkoxy, C3-7 cycloalkoxy, C3-7cycloalkyl-C1-6alkoxy, - alkyl C1- 6tio, C3-7cycloalkyl-thio, C3-7cycloalkyl-alkyl C1-6tio, - aryl, C1-6 alkyl aryl, - aryloxy, aryl-C1-6 alkoxy, - C 1-6 fluoroalkyl, C3-7 fluorocicloalquilo, fluorocicloalquil C3-7-C1-6 alkyl, - C1-6 fluoroalkoxy, C3-7 fluorociloalcoxi, fluorocicloalquil C3-7-C1-6 alkoxy, - cyano, cyano-C1-6alkyl, cyano-C1-6 alkoxy, - NRaRb , NRcCORd, NRcSO2Rd, NRcSO2NRaRb, CONRaRb, CON (ORc) Rd, - a heteroaryl group, the aryl or heteroaryl being optionally substituted with one or more substituents selected from fluorine atoms, chlorine and bromine or a C1-6 alkyl, C3-7cycloalkyl, C1-6 alkoxy, C1-6 fluoroalkyl, fluoroa C1-6 lcoxi or cyano, aryl being selected from phenyl and naphthyl, the heteroaryl group being selected from pyridyl, pyrimidinyl, pyridazinyl, pyrazinyl, triazinyl, pyrrolyl, furyl, thienyl, imidazolyl, oxazolyl, thiazolyl, pyrazolyl, isoxazolyl, isothiazolyl, oxadiazolyl , thiadiazolyl, triazolyl, tetrazolyl; Ra and Rb represent, independently of each other, a hydrogen atom or a C1-6 alkyl, C3-7 cycloalkyl or C1-6 cycloalkyl C3-7 alkyl or alternatively form with the nitrogen atom carrying them a ring chosen from azetidine, pyrrolidine, piperidine, morpholine, thiomorpholine, azepine and piperazine, this ring being optionally substituted with one or C1-6alkyl, Rc and Rd represent, independently of each other, more groups a hydrogen atom or an alkyl group C1-6, C3-7 cycloalkyl or C3-7 cycloalkyl-C1-6alkyl, in the form of the base or an acid addition salt.