Photo-Controllable Catalysis and Chiral Monosaccharide Recognition Induced by Cyclodextrin Derivatives.

A supramolecular catalytic system was constructed by polycationic α-cyclodextrin ( 6-Iz-α-CD ), gold nanoparticles ( AuNP ) based on supramolecular assembly strategy. The cavity of cyclodextrin is the channel which the substrate molecules contact with the catalytic center. Introduction of the azobenzene-modified diphenylalanine ( Azo-FF ) guest molecule allowed for photo-control of the catalytic activity precisely owing to its sensitive response to irradiation. Importantly, as unique glucose oxidase, the AuNP@6-Iz-α-CD realizes unprecedented chiral recognition catalysis for chiral monosaccharides. In combination with 3, 3, 5, 5-tetramethylbenzidine (TMB) color reaction, the AuNP@6-Iz-α-CD exhibits the ability to recognize the chirality of various monosaccharides.