Neonatal Pig Sertoli Cells Survive Xenotransplantation by Creating an Immune Modulatory Environment Involving CD4 and CD8 Regulatory T Cells.

Gurvinder Kaur,Kandis Wright,Payal Mital,Taylor Hibler,Jonathan M. Miranda,Lea Ann Thompson,Katelyn Halley,Jannette M. Dufour

Neonatal Pig Sertoli Cells Survive Xenotransplantation by Creating an Immune Modulatory Environment Involving CD4 and CD8 Regulatory T Cells.

2020

Gurvinder Kaur
Kandis Wright
Payal Mital
Taylor Hibler
Jonathan M. Miranda
Lea Ann Thompson
Katelyn Halley
Jannette M. Dufour

The acute cell-mediated immune response presents a significant barrier to xenotransplantation. Immune-privileged Sertoli cells (SC) can prolong the survival of co-transplanted cells including xenog...

Keywords:

Cell biology
CD8
Immune privilege
Biology
Immune system
Xenotransplantation
sertoli cells

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