TSPAN1 promotes autophagy flux and mediates cooperation between WNT-CTNNB1 signaling and autophagy via the MIR454-FAM83A-TSPAN1 axis in pancreatic cancer.

Cefan Zhou,Yanyan Liang,Li Zhou,Yanan Yan,Nanxi Liu,Rui Zhang,Huang Yuan,Ming Wang,Yongfei Tang,Declan W. Ali,Yefu Wang,Marek Michalak,Xing-Zhen Chen,Jingfeng Tang

TSPAN1 promotes autophagy flux and mediates cooperation between WNT-CTNNB1 signaling and autophagy via the MIR454-FAM83A-TSPAN1 axis in pancreatic cancer.

2020

Cefan Zhou
Yanyan Liang
Li Zhou
Yanan Yan
Nanxi Liu
Rui Zhang
Huang Yuan
Ming Wang
Yongfei Tang
Declan W. Ali
Yefu Wang
Marek Michalak
Xing-Zhen Chen
Jingfeng Tang

Pancreatic cancer is one of the most aggressive tumors associated with a poor clinical prognosis, weakly effective therapeutic options. Therefore, there is a strong impetus to discover new therapeu...

Keywords:

TETRASPANIN 1
Cancer research
Wnt signaling pathway
Autophagy
Biology
Pancreatic cancer
clinical prognosis

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