The synthesis of ethanolamine libraries from olefin scaffolds
2000
Abstract A solution-phase, multi-reaction sequence has been developed for the parallel synthesis of ethanolamine libraries. This approach uses 2,3-dibromopropene as a template for the synthesis of a small olefin sub-library, which is then further functionalized to form the final ethanolamine library. The methodology is demonstrated by the synthesis of a 5×4 array of ethanolamines.
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