Synthesis and biological screening of 2-(4-chlorophenyl)-6-methyl-3-(3- aryl -1-acetyl/phenyl -4,5-dihydropyrazol-5-yl)- imidazo[1, 2-a]pyridines

2009 
2-(4i‚¢-chlorophenyl)-6-methyl-3-(3i‚²-aryl-1i‚²acetyl-4i‚²,5i‚²-dihydropyrazol-5i‚²- yl)imidazo [1,2-a] pyridines (4a-4l); 2-(4'-chlorophenyl)-6-methyl-3-(3i‚²-aryl- 1i‚²-phenyl-4i‚²,5i‚² dihydropyrazol-5i‚²-yl) imidazo [1, 2-a] pyridines(5a-5l) have been synthesized. The products have been assayed for their biological activity against Gram +ve,Gram –ve bacteria and fungi. Some of the products showed moderate activity in concentration 50i­g/ml. The structures of the products have been elucidated by IR, 1HNMR, Mass spectral data, elemental analysis and thin layer chromatography.
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