Synthesis and biological screening of 2-(4-chlorophenyl)-6-methyl-3-(3- aryl -1-acetyl/phenyl -4,5-dihydropyrazol-5-yl)- imidazo[1, 2-a]pyridines
2009
2-(4i¢-chlorophenyl)-6-methyl-3-(3i²-aryl-1i²acetyl-4i²,5i²-dihydropyrazol-5i²- yl)imidazo [1,2-a] pyridines (4a-4l); 2-(4'-chlorophenyl)-6-methyl-3-(3i²-aryl- 1i²-phenyl-4i²,5i² dihydropyrazol-5i²-yl) imidazo [1, 2-a] pyridines(5a-5l) have been synthesized. The products have been assayed for their biological activity against Gram +ve,Gram Âve bacteria and fungi. Some of the products showed moderate activity in concentration 50ig/ml. The structures of the products have been elucidated by IR, 1HNMR, Mass spectral data, elemental analysis and thin layer chromatography.
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