Effects of surface modification on toxicity of CeO2 nanoparticles to lettuce

Abstract Phytotoxicity of nanoceria (nCeO2) has been reported, but there are few studies on how to reduce its phytotoxicity. In the present study, we modified nCeO2 with two organophosphates (nCeO2@ATMP and nCeO2@EDTMP) and compared their toxicity to lettuce with that of uncoated nCeO2. The results showed that bare nCeO2 significantly inhibited the root growth of lettuce, leading to oxidative damages and root cell death. In contrast, after surface modification, the toxicity of nCeO2@ATMP to lettuce was weakened, while nCeO2@EDTMP was nontoxic to lettuce. It was found that the surface properties of the modified materials have been changed, resulting in sharp decreases in their bioavailability. Although nCeO2 with and without surface coatings were all transformed when interacting with plants, the absolute contents of Ce(III) in roots treated with modified nCeO2 decreased significantly, which may be the main reason for the reduction of toxicity. This study indicates that it is feasible to reduce the phytotoxicity of nanomaterials through surface coating.