Synthetic studies toward the disorazoles: synthesis of a masked northern half of disorazole D1 and a cyclopropane analog of the masked northern half of disorazole A1
2003
Abstract The synthesis of a masked northern half of the natural product disorazole D 1 and a cyclopropane analog of the masked northern half of disorazole A 1 is described. The synthesis involves in both cases as key steps a Z -selective Wittig olefination and a Sonogashira cross-coupling reaction.
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