HLA—A, —B, and —D Antigens in Paralytic Poliomyelitis

Sixty-two unrelated Caucasian patients from the Munich area who had had paralytic poliomyelitis in the 1950s and the early 1960s were analyzed. HLA—A and —B typing was performed for 26 antigens. HLA—D typing was done using six different established homozygous typing cells defining the specificities Dw1-Dw5 and Dw11, plus one locally defined typing cell. None of the HLA—A, —B or —D determinants showed a significant deviation in frequency from control populations. Of interest may be a decrease of B8 and an increase of Bw16 (Bw38/39) and B27, but these deviations are not significant if their P values are corrected for the number of comparisons made.