Pericyte degeneration leads to neurovascular uncoupling and limits oxygen supply to brain
2017
The role of pericytes in the regulation of cerebral blood flow (CBF) and neurovascular coupling remains unclear. Using loss-of-function pericyte-deficient mice, the authors report that pericyte degeneration reduces CBF responses to neuronal stimuli and oxygen supply to the brain, leading to metabolic stress, neuronal dysfunction and neurodegeneration.
Keywords:
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
64
References
246
Citations
NaN
KQI