Iron(III) chloride catalyzed glycosylation of peracylated sugars with allyl/alkynyl alcohols

Neste trabalho, o emprego de cloreto ferrico como um eficiente catalisador em reacoes de glicosilacao de acucares na presenca de alcoois alilicos e propargilicos e descrito. Os glicosidios correspondentes foram obtidos com rendimentos de moderados a bons. Este novo procedimento apresenta maior seletividade quando comparado a metodos classicos encontrados na literatura. As principais caracteristicas desse metodo simples incluem condicoes de reacao nao perigosas, quantidade de catalisador baixa, bom rendimento e seletividade anomerico elevada. In this work, the use of ferric chloride as an efficient catalyst in glycosylation reactions of sugars in the presence of allyl and alkynyl alcohols is described. The corresponding glycosides were obtained with moderate to good yields. This new procedure presented greater selectivity when compared to classic methods found in the literature. Principal features of this simple method include non-hazardous reaction conditions, low-catalyst loading, good yields and high anomeric selectivity.