Identification of Differentially Expressed mRNAs of the Autologous Vein Graft After an Arterial Bypass in Mongrel Dogs

Purpose. Intimal hyperplasia (IH) is characterized by vascular smooth muscle cell (VSMC) proliferation in the intima and subsequent accumulation of extracellular matrix. A variety of factors that might be considered as possible VSMC mitogens induce the specific gene expression of VSMC. This study was designed to identify differentially expressed mRNA by method using an mRNA differential display.