Transcription factors FOXO in the regulation of homeostatic hematopoiesis
2018
Purpose of review
Work in the past decade has revealed key functions of the evolutionary conserved transcription factors Forkhead box O (FOXO) in the maintenance of homeostatic hematopoiesis. Here the diverse array of FOXO functions in normal and diseased hematopoietic stem and progenitor cells is reviewed and the main findings in the past decade are highlighted. Future work should reveal FOXO-regulated networks whose alterations contribute to hematological disorders.
Keywords:
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
95
References
12
Citations
NaN
KQI