Preliminary evidence from microsatellite and 2La inversion polymorphism suggests DDT resistance drives genetic differentiation between populations of Anopheles gambiae s.s. in South West Nigeria

Background Resistance to the insecticide DDT has emerged in several Anopheles gambiae populations which has stalled its use in malaria vector control programs in Nigeria. Data on insecticide resistance in Nigeria are still patchy with consequent lack of understanding of resistance mechanisms. This study was therefore designed to investigate the relationship between DDT resistance, inversion 2La and microsatellite loci in Anopheles gambiae s.s. populations from Lagos and Oyo State, South West, Nigeria.