Fire-Diffuse-Fire Calcium Waves in Cylindrical Intracellular Spaces

Propagation of fire-diffuse-fire Ca2+ waves through a cylindric domain is considered.Ca2+ concentration is an analytic solution derived from the diffusion equation in the domain.Existence and stability are shown to be dependent on the radius and the Ca2+ pump rate.It is also shown that the threshold of fire increase as radius increasing in finite interval.The results provides better understanding about the roles of endoplasmic and Ca2+ pumps in the intracellular Ca2+ dynamics of cells.