TfOH-Promoted Decyanative Cyclization toward the Synthesis of 2,1-Benzisoxazoles.
2021
A novel solvent-free, TfOH-promoted decyanative cyclization approach for the synthesis of 2,1-benzisoxazoles has been developed. The reactions are complete instantly at room temperature and result in the formation of the desired 2,1-benzisoxazoles in a 34-97% isolated yield.
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