Inactivation of Rheb by PRAK-mediated phosphorylation is essential for energy-depletion-induced suppression of mTORC1
2011
Under conditions of energy starvation, the p38β–PRAK pathway is activated and inhibits mTORC1 by phosphorylating the small GTPase Rheb. This finding links a major stress response pathway with energy homeostasis.
Keywords:
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
54
References
110
Citations
NaN
KQI