The AGC kinase SGK1 regulates TH1 and TH2 differentiation downstream of the mTORC2 complex
2014
The kinase SGK1 is a downstream target of mTORC2 signaling. Powell and colleagues show that SGK1 regulates TH2 polarization by increasing the stability of the transcription factor JunB and antagonizing IFN-γ expression.
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