Novel suction-based in vivo cutaneous DNA transfection platform.

Emran O. Lallow,Nandita C. Jhumur,Ijaz Ahmed,Sagar B. Kudchodkar,Christine C. Roberts,Moonsup Jeong,Juliet M. Melnik,Sarah H. Park,Karuppiah Muthumani,Jerry W. Shan,Jeffrey D. Zahn,David I. Shreiber,Jonathan P. Singer,Young Kyoung Park,Joel N. Maslow,Hao Lin

Novel suction-based in vivo cutaneous DNA transfection platform.

2021

Emran O. Lallow
Nandita C. Jhumur
Ijaz Ahmed
Sagar B. Kudchodkar
Christine C. Roberts
Moonsup Jeong
Juliet M. Melnik
Sarah H. Park
Karuppiah Muthumani
Jerry W. Shan
Jeffrey D. Zahn
David I. Shreiber
Jonathan P. Singer
Young Kyoung Park
Joel N. Maslow
Hao Lin

This work reports a suction-based cutaneous delivery method for in vivo DNA transfection. Following intradermal Mantoux injection of plasmid DNA in a rat model, a moderate negative pressure is appl...

Keywords:

Molecular biology
In vivo
plasmid dna
2019 20 coronavirus outbreak
Coronavirus disease 2019
severe acute respiratory syndrome coronavirus 2
Chemistry
rat model
dna transfection
suction

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