Synthesis and Antifungal Activity Against Candida Albicans of 6-Aryl-3,4-Dimethyl-N-Phenyl-2-Oxo-1,2,3,6-Tetrahydropyrimidine-5-Carboxamides
2015
6-Aryl-3,4-dimethyl-N-phenyl-2-oxo-1,2,3,6-tetrahydropyrimidine-5-carboxamides were synthesized by three-component reactions of acetoacetanilide, aromatic aldehydes, and N-methylurea. The structures of the compounds were confirmed by IR and PMR spectroscopy and mass spectrometry. The antifungal activity of the synthesized compounds was studied.
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