Novel insecticides: A potential tool for the management of insect pest

Development of selective properties insecticides that act on biochemical sites present in particular insect groups, but their properties are different from other insecticides. Aim of this study is the discovery of compounds that affect the hormonal regulation of molting and developmental processes in insects viz., ecdysone agonists (tebufenozide and methoxyfenozide), juvenile hormone mimics (pyriproxyfen and fenoxycarb), and chitin synthesis inhibitors (benzoylphenyl ureas and buprofezin). Insect nicotinic acetylcholine receptor such as imidacloprid, acetamiprid, and thiamethoxam has been introduced for the control of aphids, whiteflies, and other insect species. Novel compound pyradalyl (S-1812) has found to act selectively on lepidopterans and thrips. Neuroactive chemicals have played major role in management of insect pests in crops, their judicious uses led to several problems like insect resistance, secondary pest outbreaks, destruction of natural enemies’, residue and resurgence. Now days the focus is laid down on development of new green chemistries insecticides having novel biochemical target for controlling pest, understand mode of action and resistance management. The mechanism of these insecticides targeting of a molecular target site present in pest on an enzyme form that is different from other organism. In recent years, several new insecticide groups having new chemistries viz., neonicotinoids, oxadiazines, diamides etc. are developed and commercialized for controlling pest. Novel insecticides will play a greater role in controlling pest because they are target specific in pest having no toxicity on non-target pest (environment friendly and toxicologically safer), high efficiency in pest control, and resistance management.