Antidepressant compound, method for preparing same and application

The invention discloses an antidepressant steroidal compound, a method for preparing the same and application. The structure of the antidepressant steroidal compound which is a derivative is shown asa formula I. Various substituent groups in the antidepressant steroidal compound are defined in the specification and the claims. The antidepressant steroidal compound can be used for preventing, managing, treating or relieving diversified diseases and symptoms such as depression.