A New Synthesis for the Monobactam Antibiotic - LYS228.

Zhongbo Fei,Quanbing Wu,Lei Li,Qun Jiang,Bin Li,Like Chen,Hao Wang,Bin Wu,Xianwen Wang,Feng Gao,Wenlong Qiu,Jing Guo,Chi Ming Cheung

A New Synthesis for the Monobactam Antibiotic - LYS228.

2020

Zhongbo Fei
Quanbing Wu
Lei Li
Qun Jiang
Bin Li
Like Chen
Hao Wang
Bin Wu
Xianwen Wang
Feng Gao
Wenlong Qiu
Jing Guo
Chi Ming Cheung

ABSTRACT: A new synthesis of LYS228, fitting for further process development for commercial manufacture is described. The key features of the synthesis include development of new protocols for acyl...

Keywords:

Monobactam
Organic chemistry
Antibiotics
Chemistry
key features
process development
Acylation

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