Fibroblast growth factor-21 enhances mitochondrial functions and increases the activity of PGC-1alpha in human dopaminergic neurons via Sirtuin-1

Johanna Mäkelä,Timofey V. Tselykh,Francesca Maiorana,Ove Eriksson-Rosenberg,Hai Thi Do,Giuseppa Mudò,Laura Korhonen,Natale Belluardo,Dan Lindholm

Fibroblast growth factor-21 enhances mitochondrial functions and increases the activity of PGC-1alpha in human dopaminergic neurons via Sirtuin-1

2014

Johanna Mäkelä
Timofey V. Tselykh
Francesca Maiorana
Ove Eriksson-Rosenberg
Hai Thi Do
Giuseppa Mudò
Laura Korhonen
Natale Belluardo
Dan Lindholm

Mitochondrial dysfunctions accompany several neurodegenerative disorders and contribute to disease pathogenesis among others in Parkinson's disease (PD). Peroxisome proliferator-activated receptor ...

Keywords:

Peroxisome
Cell biology
Disease
disease pathogenesis
Sirtuin 1
Biology
FGF21
Receptor
Dopaminergic

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