Quick combination multi-mode ionization source for mass spectrometers

A mass spectrometer (10) with a multiple mode ionization source (100) for ionizing a liquid sample into at least two different modes in a single analysis by mass spectrometry comprising: an ion chamber (160) which defines an ion path and disposed in fluid communication with a vacuum in a housing (30) mass analyzer (35, 34, 32, 31); surrounds the multi-mode ionization source (100) that includes a source chamber (101) that defines an ionization at atmospheric pressure, of an electrospray probe (110) for an electrospray ionization (ESI) and a corona discharge tip (120) for chemical ionization (APCI) , further an ion inlet port (19) to the ion chamber (160), a plurality of Blockheizeinrichtungen (182) for heating the Ionisierungsbereichs, a Sondenheizeinrichtung (186) and a sample source (180), which (via a liquid inlet line (181) with the electrospray probe 110 ) connected is; a sputtering source (170) to provide an atomizing gas to the electrospray probe (110), wherein the sputtering gas is supplied at ambient temperature; wherein the electrospray probe (110) comprises a capillary tube (111) and is provided to ionize the liquid sample by electrospray ionization mode in a first of the at least two different ionization modes; and ...