HPLC DETERMINATION AND STABILITY TEST OF CAPSULES AND CHEWABLE TABLETS CONTAINING VITAMIN E MICROCAPSULES

A reversed-phase HPLC was used to assay the capsules and the chewable tablets of vitamin E microcapsules with Zorbax ODS column. The mobile phase was methanol, monitored by UV detector at 285nm. The mean recovery and RSD of the two preparations were 99.32%, 99.72% and 0.58%, 0.61%,respectively. The method was rapid, simple and reproducible. The stability of the two preparations was satisfactory after acceleration tests.