Parâmetros de metabólitos bioquímicos em ovinos criados no Brasil

The objective was to define reference intervals for values of energetic, protein, and enzymatic metabolites in sheep. The data used came from several experiments carried out between 2006 and 2018, in several higher education and research institutions. A diversified database was used with observations of sheep of different breeds, genotypes, ages and physiological categories, created in different management systems. All animals used were healthy and data from animals that showed any clinical manifestations were discarded. In order to determine the metabolic energy profile, glucose, cholesterol, triglycerides, fructosamine, HDL (high density lipoprotein), LDL (low density lipoprotein) and VLDL (very low density lipoprotein) data were obtained; for the protein profile, data on total proteins, uric acid, urea, albumin and creatinine; and for the enzymatic profile, AST (aspartate aminotransferase), GGT (gamma glutamyl transferase) and AP (alkaline phosphatase) data. Laboratory analyzes were carried out on the Bioplus© semiautomatic biochemical analyzer model, Bioplus©, and automatic biochemistry analyzer, model PKL-125, MHLab®. For the estimation and determination of the reference values, the RefVal 4.11 program was used, and the outliers values ​​were removed from the evaluation. After determining the reference values, the data obtained were compared with international tables established in the literature, and it is possible to observe that the intervals found in this work were broader, covering better results obtained in experiments carried out in Brazil.