Dependence of Erythrocyte Shape Parameter on the Low Dose γ-Irradiation

In this work it is experimentally shown that depending on the dose of irradiation the shape parameters of erythrocytes population of peripheral blood exhibit specific changes in the early post-radiation period. As a result of low dose irradiation (35μSv/h) during 5 minute by 226Ra, the rigidity of erythrocytes membrane was occurred, which was accompanied by the decreasing of cell area. In case of longer irradiation (15 minute) the instability of membrane was occurred in reswelling manner but membrane rigidity was maintained. Thus, such erythrocyte parameters as area and perimeter cannot characterize the state of erythrocyte. According to that, a new shape parameter (α) was suggested by us to assess the state of erythrocyte. It correlates those two parameters and provides the opportunity to determine more accurately the dose dependent shape changes of erythrocytes.