Interaction of Lipoproteins and Apoproteins with Bilayer Lipid Membranes

Elucidation of the mechanisms of interaction of plasma lipoproteins (LPs) with cell membranes is one of the key problems for the understanding of the processes of lipid transport into the wall under physiological conditions and in developing atherosclerosis. The existing concepts on the atherogenic role of very low and low density LP (VLDL and LDL) bringing exogenous lipids, including cholesterol, to the cells [1], and on the antiatherogenic role of high density LP (subclasses HDL2 and HDL3) carrying it away [2], presume different types of interaction with membranes by LPs of different classes.