Circulating tumor cell detection chip and application thereof

The invention relates to a circulating tumor cell detection chip and an application thereof. The above micro-fluidic chip is combined with deterministic lateral displacement and specific bio-affinity identification principles to realize synergistic high-efficiency and high-purity capturing and detection of circulating tumor cells in peripheral blood. A triangular microcolumn array modified with affinity identification molecules, such as a nucleic acid aptamer or antibody, and having a specific geometric arranging shape, is designed in the micro-chip. The rotating angle, the distance, the offset angle and other parameters of triangular arrays are regulated to control the flow behaviors of different dimensions going through micro-channels. The chip can realize three functions in order to improve the capture efficiency and the purity of the circulating tumor cells. A gas-driven sample introduction system is also designed in the invention, and can realize simultaneous control of a plurality of fluid paths through one gas pressure path.