A novel phosphodiesterase inhibitor, T-440: possible management of eosinophilic inflammation by down-regulation of interleukin-5 production.

Osamu Kaminuma,Akio Mori,Matsunobu Suko,Yoko Nishizaki,Hideo Kikkawa,Katsuo Ikezawa,Hirokazu Okudaira

A novel phosphodiesterase inhibitor, T-440: possible management of eosinophilic inflammation by down-regulation of interleukin-5 production.

1996

Osamu Kaminuma
Akio Mori
Matsunobu Suko
Yoko Nishizaki
Hideo Kikkawa
Katsuo Ikezawa
Hirokazu Okudaira

The effect of T-440, a selective type IV phosphodiesterase (PDEIV) inhibitor, on interleukin (IL)-5 production by peripheral blood mononuclear cells (PBMCs) of atopic asthmatic subjects was investigat

Keywords:

Inflammation
Immunology
Eosinophil
Interleukin 5
Phosphodiesterase inhibitor
Interleukin
Cytokine
Peripheral blood mononuclear cell
Phosphodiesterase
Biology

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