Asymmetric Transamination of α-Keto Acids Catalyzed by Chiral Pyridoxamines
2016
A new type of novel chiral pyridoxamines 3a–g containing a side chain has been developed. The pyridoxamines displayed catalytic activity and promising enantioselectivity in biomimetic asymmetric transamination of α-keto acids, to give various α-amino acids in 47–90% yields with up to 87% ee’s under very mild conditions. An interesting effect of the side chain on enantioselectivity was observed in the reaction.
Keywords:
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
72
References
16
Citations
NaN
KQI